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Ongoing Global Research Initiatives 

Continued efforts are being made to validated Longvida® Optimized Curcumin. Clinical trials are both NIH and privately funded.


If you are interested in learning more about our research, or are interested in conducting research, please contact us!​

Archive research & news

Longvida® Optimized Curcumin Receives US PATENT 9,192,644

November 24, 2015, NOBLESVILLE, Ind. – Verdure Sciences’ Longvida® Optimized Curcumin was awarded the US Patent 9192644 by the United States Patent Office for “Curcuminoid formulations having enhanced bioavailability…”, as discovered by researchers with UCLA. 
The awarded patent now accompanies EP Patent 1993365 to further validate Longvida® Optimized Curcumin. The basis for the US Patent was long list of university and clinical research, as well as international research, that expands upon the original patent.. 

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CURCUMIN SUPPLEMENT IMPROVES VASCULAR ENDOTHELIAL FUNCTION IN MIDDLE-AGED AND OLDER ADULTS

Mounting evidence suggests that curcumin, an ingredient in the Indian spice turmeric, has vascular protective effects in aging animals and humans. We tested the hypothesis that curcumin improves vascular endothelial function, as assessed by endothelium-dependent dilation (EDD), in middle-aged and older (MA/O) adults (45-74 yrs) by...

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latest research & news

Reduced inflammatory & muscle damage biomarkers after supplementation with bioavailable Curcumin 

The purpose of this study was to determine the effects of oral

supplementation of Longvida® 400 mg/days on muscle & ADL soreness, creatine kinase, and inflammatory cytokines following EMID. Subjects were randomly assigned to either curcumin or placebo (rice flour) and supplemented 2 days before to 4 days after EMID. Blood samples were collected prior to, and 1, 2, 3, and 4 days after EIMD to measure CK and inflammatory cytokines. Curcumin supplementation resulted in significantly smaller increases in CK (− 48%), TNF-α (− 25%), and IL-8 (− 21%) following EIMD compared to placebo. Continue Reading

Choosing the right Curcumin Supplement

The question is not if curcumin should be in your supplement, but which curcumin should be in your supplement. When curcumin is consumed, it converts into metabolites such as curcumin glcuronide, which is often incorrectly marketed as curcumin.

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Verdure Sciences, Inc © 2016 ALL RIGHTS RESERVED. 

Verdure Sciences, Longvida (US Patent 9192644, EP Patent 1993365; additional patents pending), Bacognize, Calzbone, Pomella (US Patents 7638640, 7897791, and 7919636; EP Patent 1734949; additional patents pending), Tinofend, and WokVel are registered trademarks of Verdure Sciences, Inc. Cinnagest, Factor21, Lutevida, Rejuna, Thymocid, Gingerize, VBATS, VerdeMedica, SLP, and SLCP are trademarks of Verdure Sciences, Inc. All Rights Reserved. © 2016 Verdure Sciences.

References

-Biomarkers: Curcumin supplement improves vascular endothelial function in middle-aged and older adults. Santos-Parker JR et al. Geront. Dec 2015. 55(Suppl 2): 195. DOI:10.1093/geront/gnv554.01

-Longvida® Curcumin & Recovery from Muscle Injury, University of North Texas, Complete Awaiting Publication

-Anti-Inflammatory Effects of Novel Standardized Solid Lipid Curcumin Formulations. Nahar PP et al. University of Rhode Island, J Med Food. July 2015. 18(7): 786-792. doi:10.1089/jmf.2014.0053

-Investigation of the effects of solid lipid curcumin on cognition and mood in a healthy older population. Cox et al. Centre for Human Psychopharmacology, Swinburne University. J Psychopharmacol May 2015. (Vol 29)No 5: 642-651. doi: 10.1177/0269881114552744​

-Anti-inflammartory effects of novel standardized solid lipid curcumin formulations. Nahar et al, J Med Food. 2014. 1-7.         
-Investigation of the effects of solid lipid curcumin on cognition and mood in a healthy older population. Cox et al 2014, J Psychpharm. 2014 Oct 2. 

-Curcumin (Longvida®) suppresses soluble tau oligomers and corrects molecular chaperone, synaptic and behavioral deficits in aged human tau transgenic mice. Ma et al, J Biol Chem. 2013 Feb 8;288(6):4056-65. doi: 10.1074/jbc.M112.393751.   

-Acute human pharmacokinetics of a lipid-dissolved turmeric extract. Shah et al. Planta Med 2012; 78-PH5       
-Diverse effects of a low-dose supplement of lipidated curcumin (as Longvida®) in healthy middle-aged people. Disilvestro et al. The Ohio State University. Nutr J. 2012. 26;11:79. doi 10.1186/1475-2891-11-79
-Effects of Longvida® on soluble tau oligomers and cognitive and synaptic deficits. Frautschy et al. AAIC 2011, Paris France.              
-Human pharmacokinetics of chronic dosing of Longvida®: dose-concentration correlation. UCLA, 2011.
-Acute human pharmacokinetics of 40mg curcumin (as Longvida®) leads to therapeutic blood levels. Shah et al. Manuscript submitted 2011.
-Efficacy of Longvida® in stage III human trials, TATA Memorial Centre, Mumbai. Study ongoing.
-Impact of Longvida® on soluble tau oligomers and behavioral and synaptic impairment. Ma et al 2011. Manuscript in publication.                          

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Mellow yellow? the mood and cognitive effects of curcumin from turmeric

Curcumin is the component of turmeric (Curcuma longa) that gives the spice its bright yellow colour. It is one of more than 5,000 flavonoids, a group of plant-based compounds thought to contribute to the health benefits of fruit and vegetables. 

The purported medical effects of curcumin have a long history, going back at least to the 18th centruy. In 1937, a paper in the Lancet medical journal described successful case studies using curcumin in the treatment of inflamed gall bladders.

Around 150 curcumin studies are under way to investigate the effects of curcumin (alone or in combination with other drugs...

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Please note that the physiological activity of the ingredient(s) described herein is supported by the referenced clinical trial report(s). Marketers of finished products containing the ingredient(s) described herein are responsible for determining whether claims made for such products are lawful and in compliance with the laws of the country in which they will market the products.​