Longvida Selected Data


Data from more than a dozen research studies supports Longvida’s safety and efficacy for supporting healthy aging and cognitive health.*  
Recently, in preclinical and clinical trials, just 80mg of curcumin (as Longvida®) showed significant benefits impacting health in just 30 days (see below video for a more detailed discussion).


This clinical data is consistent with human pharmacokinetics (bioavailability) data, where Longvida was 65 times more bioavailable than unformulated curcumin based on Cmax, and more than 100 times more bioavailable based on Area Under the Curve (AUC).  One groundbreaking finding over the course of several bioavailability studies using different doses, is that dosing of Longvida leads to therapeutic levels of free (not inactivated or glucuronidated) curcumin in the bloodstream and target tissues.

Shortly after the discovery of Longvida®, a groundbreaking study from UCLA published in the Journal of Pharmaceutics and Experimental Therapeutics (JPET) in 2008 wrote about Longvida®: "This suggests oral delivery can achieve our target tissue levels."  

(See a list of Scientific References on Longvida.)




Then, work from UCLA subsequently discovered that dosing of Longvida offers therapeutic target concentrations of curcumin in the brain, in addition to other blood and tissue compartments (see below).  























Later, a number of studies revealed chronic dosing of Longvida could impact biochemical and behavioral endpoints in the brain (below).




Neurogenesis, the regeneration of new brain cells, is the focus of much of the work on Longvida.  New findings indicate chronic dosing of Longvida may support healthy synaptic function in the brain (below).  



Behavioral data is consistent with biochemical and gene expression data (selected data below).







Although it may be difficult to determine which form of curcumin is the best, there are some key Questions to Ask.  Also, be sure to check out the Scientific References on Longvida.

   

* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Please consult your healthcare practitioner before taking any medication or health supplements.

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